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When a search space has irreducible complexity, ensemble search methods can improve performance. It's possible culture, emotions, religion, etc are part of an ensemble.

Simulating the "human search method" in silico doesn't need to include specific personalities, but they do provide a bootstrap, just as we've bootstrapped current AI with human language.

For symbiosis, there may be an advantage to the physical adaptability of biology.

In general, it's currently unclear if biology is emulating what we're creating in computers, if computers are emulating what we achieve biologically, or if both approaches are imperfect emulations of a different ideal search method.


If this is true, what prevents a fully computer search from adding noise, branching or in general simulating diversity with evolutionary methodology, much more efficiently than humans?


Without humans, you could rediscover any benefit the "human search method" confers with enough compute and time, but we're limited by both.


That's quite a complement to AI


We have already seen selection pressure results in Candida auris

https://journals.asm.org/doi/10.1128/mbio.01397-19 (2019)

https://radiolab.org/podcast/fungus-amungus (2020)


It can be airborne, lives on sanitized surfaces for up to 10 weeks, and may take 3 years for symptoms to appear.

Still, it is more concerning for cats than humans.


Hypochlorous acid (HOCl) is highly effective at killing Sporothrix fungi, including Sporothrix brasiliensis

HOCl is the best non-toxic broad spectrum human compatible antimicrobial. I have been using it in many household applications since COVID started.

It can be prepared by electrolysis of acidified (e.g. vinegar, but ideally pH 5.5, and inorganic acids make it last way longer at that pH, but they are more dangerous to handle) salt water (high margin of safety) or alternatively prepared by mixing highly diluted bleach with an diluted acid (low margin of safety) to target 20-2000 ppm depending on your delivery method (e.g. one tablespoon of bleach and vinegar into a gallon of water). If you are worried about the safety of this approach, note that far, far less chlorine gas is emitted when made this way than by ordinary bathroom cleaning with a bleach-based bathroom cleaner.

The smell of HOCl is unique and completely different from chlorine gas. The small amount of chlorine gas emitted likes to sit on top of the surface of the water, but if this layer is blown away, the distinct smell of HOCl becomes apparent immediately. It smells like minty bubblegum or something more familiar: a swimming pool.

The good news is when making HOCl for disinfection purposes 20-2000 ppm, only very small quantities of chlorine gas are evolved. They can be reduced further by shaking the closed container used to make it, further dissolving the gas into solution to make more HOCl.

I run this solution in my humidifier at low concentrations to prevent microorganisms from growing in it. I also use the electrolysis method to accurately make very low concentrations for nasal rinses. Typically, 15-30 seconds from a $10 USB electrolyzer in salt water.


"AI Overview" blithely tells me HOCL can be easily made from the electrolysis of salt water.

Looking even a little deeper (Wikipedia) confirms that chlorine chemistry, especially when combined with electrolysis, is very complex, and it's hard to know if you're making the right thing. FWIW every sensible electrolysis-based DIY project has dire warnings about electrolysing solutions of common salt.


> it's hard to know if you're making the right thing

In this case, it's not complicated


Please don't tell me you're recommending that people smell their DIY chlorine chemistry to determine what they've made?


There is no problem at 200 ppm. Skill issue


You're saying that as long as it proceeds as expected, then all will be ok. In the worst case (eg, at the 2,000ppm you indicate as an upper range, or after some mis-step in the process), what ppm chlorine gas would be created, and what would happen if you got a noseful of that at close quarters?

This is just terrible advice.


Looks like HOCL generators are household appliances now.


Hypochlolorous acid, otherwise known as "swimming pool water"


From my experience, the team that's the closest to open-source pixel-perfect Word support is https://github.com/superdoc-dev/superdoc (unaffiliated)


One argument may be that ownership is the last role for a human in a business. The firm exists to show ownership of an AI and provides a mechanism for managing its proceeds.


Derek Muller of Veritasium has a presentation on why the promises of a revolution in education are never fulfilled. [0]

His hottest take is we're already close to the optimal process for learning, so technology isn't going to improve it. Learning takes work, and no technology can do the work for you.

[0] https://www.youtube.com/watch?v=0xS68sl2D70


Nanoclaw uses the official claude agent sdk, so it should be unaffected.


For those looking for an MIT alternative, there's an embeddable solution which uses PDFium (Apache) compiled to wasm instead of MuPDF (AGPL): https://www.embedpdf.com/

There's a hosted version for quick edits: https://app.embedpdf.com/

Discussion from several months ago: https://news.ycombinator.com/item?id=44901683

Neither fully handles XFA, but that's a perennial struggle.


> A recent study from Stanford

Source?


A recent study from Stanford


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